NeoRad Breast Cancer Study
ConditionBreast Cancer
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age18+
SponsorBielefeld University
About this trial
The NEORAD trial tests whether preoperative radiotherapy results in an improved DFS and less radiation induced late effect compared to postoperative radiotherapy in higher risk breast cancer after NACT.
Eligibility criteria
Qualifiers
Histologically proven invasive, unilateral breast cancer
Indication for radiotherapy
Indication for neoadjuvant chemotherapy (+/- antibody treatment or other targeted therapies) in accordance with national and international guidelines
Female
Disqualifiers
Neoadjuvant treatment solely with endocrine therapy
Bilateral breast cancer
Pregnancy or lactation
Prior radiotherapy of the thorax
Trial design
Treatments tested in this trial
- preoperative radiotherapy
- postoperative radiotherapy
Treatment groups
1,826 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov