Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNE

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age6-18
SponsorMansoura University

About this trial

The goal of this clinical trial is to compare combination of Solifenacin and MIrabegron in treatment of primary mono-symptomatic nocturnal enuresis in children. It will also learn about the safety of that combination. The main questions it aims to answer are:

Does combination of Solifenacin and MIrabegron lower the number of wet nights? What medical problems do participants have when taking combination of Solifenacin and MIrabegron? Researchers will compare the combination to omegapress to see if the combination works better to treat primary mono-symptomatic nocturnal enuresis.

Participants will:

Take the combination or Omegapress every day for 3 months Visit the clinic once monthly for checkups and tests Keep a diary of their symptoms and the number of wet nights

Eligibility criteria

Qualifiers

None

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Mirabegron (beta3-adrenoceptor agonist), Anticholinergics
  • Desmopressin (DDAVP)

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators