Opioid-Sparing Joint Replacement
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorEmory University
About this trial
The goal of this clinical trial is to evaluate whether an opioid-sparing postoperative pain regimen can reduce opioid consumption and maintain effective pain control in adults undergoing anterior total hip arthroplasty for osteoarthritis.
The main questions it aims to answer are:
* Does an opioid-limited regimen result in lower postoperative opioid use compared with a standard opioid prescription? * Does the opioid-limited regimen provide comparable or improved postoperative pain control and patient satisfaction?
Eligibility criteria
Qualifiers
Diagnosis of hip osteoarthritis requiring primary arthroplasty
Scheduled to undergo anterior total hip arthroplasty (THA)
Able to comply with study procedures and follow-up visits
Able to provide informed consent
Disqualifiers
Concurrent significant injuries to other bones or organs
Local infection at or near the surgical site
Preoperative opioid use within 4 weeks prior to surgery
History of severe heart disease (NYHA Class II or higher), renal failure, or liver dysfunction
Trial design
Treatments tested in this trial
- Placebo
- Oxycodone 5 mg
- Multimodal Non-Opioid Analgesia
Treatment groups
120 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov