Phase 3 Study of JP-1366: Efficacy and Safety of JP-1366 in Patients With Non-erosive Gastroesophageal Reflux Disease

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age19-75
SponsorOnconic Therapeutics Inc.

About this trial

This study aims to evaluate the efficacy and safety of JP-1366 in Patients with NERD

Eligibility criteria

Qualifiers

Subjects who have experienced both heartburn and acid regurgitation

Subjects in whom no mucosal breaks were observed on upper GI endoscopy at Visit 1 by LA Classification

Subjects who fully understand this clinical trial and voluntarily signed the informed consent form

Disqualifiers

Subjects who have significant gastrointestinal diseases or procedures affecting the esophagus, stomach, or duodenum

Subjects who have a history of recent substance abuse, malignancy, systemic autoimmune or immune deficiency diseases, refractory response to PPI/P-CAB, hypersensitivity to study drugs, genetic metabolic disorders, or significant psychiatric conditions.

Subjects who showed clinically significant abnormalities in laboratory tests

Positive result in the H. pylori test

Trial design

Treatments tested in this trial

  • JP-1366 + placebo
  • Placebo + Placebo

Treatment groups

321 Participants
are divided into 3 treatment groups

Locations

This trial has no locations

Sponsors and collaborators