Premedication on Post-endodontic Pain
ConditionPremedication
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age20-50
SponsorGulf Medical University
About this trial
The goal of this clinical trial is to compare the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis. The main question it aims to answer is:
What is the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis? Participants will undergo root canal treatment after premedication. Researchers will compare \[alpha-chemo-trypsin, ibuprofen, and acetaminophen\] to see the intensity of post-endodontic pain.
Eligibility criteria
Qualifiers
Eligibility for root canal treatment Patients diagnosed with symptomatic irreversible pulpitis with normal apical tissue in mandibular molars
Disqualifiers
• Patient under any medication or analgesic intake for pain management.
Patients with any systemic health issues
Patient allergies to trypsin-chymotrypsin, ibuprofen, and paracetamol
Pregnancy.
Trial design
Treatments tested in this trial
- Root canal treatment
Treatment groups
48 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov