Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter
ConditionHyperthyroidism
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-75
SponsorJan Calissendorff
About this trial
The purpose of this study is to assess if preoperative treatment with Lugol's solution prior to thyroidectomy can reduce the surgical complications hypoparathyroidism and laryngeal nerve palsy
Eligibility criteria
Qualifiers
Hyperthyroidism accepted for thyroidectomy due to toxic nodular goiter with free T4 <30 pmol/L or Graves' disease
Signed informed consent
Disqualifiers
Unstable coronary artery disease
Previous thyroid surgery
Congestive heart failure
Renal insufficiency
Trial design
Treatments tested in this trial
- Iodine-Potassium Iodide 5%-10% Oral and Topical Solution
Treatment groups
182 Participants
are divided into 2 treatment groupsSponsors and collaborators
Jan Calissendorff
Lead sponsor
Karolinska University Hospital
Sponsor institution
Source ClinicalTrials.gov