Progesterone-modified Natural Cycle for FET
ConditionInfertility, Female
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age21-44
SponsorShandong University of Traditional Chinese Medicine
About this trial
Hormone replacement therapy (HRT) cycles, despite the ease of synchronizing embryo thawing and embryo transfer timing, increase the risk of pregnancies and obstetric complications compared to natural cycles (NC). By ensuring the presence of the corpus luteum while reducing the number of monitoring sessions, the progesterone modified natural cycle (P4mNC) offers more convenience for the patient than the normal NC. This study is designed to compare the effects of P4mNC and HRT cycles on FET outcomes.
Eligibility criteria
Qualifiers
Patients aged 21 to 44 years undergoing FBT
Body mass index (BMI) 18-35 kg/m2
Having regular ovulatory cycles
Disqualifiers
Untreated uterine adhesions
Medical contraindications to estrogen and progesterone therapy
Illnesses contraindicating assisted reproductive technology or pregnancy
History of recurrent implantation failures (> 2 embryo transfer failures)
Trial design
Treatments tested in this trial
- Progesterone-modified natural cycle preparation for frozen embryo transfer
- Hormone replacement therapy cycle preparation for frozen embryo transfer
Treatment groups
336 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov