PRP in ACLR to Prevent PTOA
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age14-50
SponsorHospital for Special Surgery, New York
About this trial
The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.
Eligibility criteria
Qualifiers
Acute ACL injury within 6 weeks of presentation
Age 14-50
Male or female
Meniscus injury that can be treated with meniscectomy or repair (the lack of meniscus injury will not exclude patients)
Disqualifiers
Prior ACL reconstruction
Prior cartilage repair procedure
Prior meniscus surgery within 12 months
Prior steroid, hyaluronic acid, or PRP injection within 6 months
Trial design
Treatments tested in this trial
- platelet rich plasma (PRP) injection
- placebo saline injection
Treatment groups
56 Participants
are divided into 2 treatment groupsSponsors and collaborators
Hospital for Special Surgery, New York
Lead sponsor
Orthopedic Research and Education Foundation
Collaborator
Source ClinicalTrials.gov