Safety Outcomes Post Kidney Biopsy - Randomized Clinical Evaluation of Efficacy of Desmopressin

ConditionKidney Biopsy
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-99
SponsorMedical University of Bialystok

About this trial

It is a randomized, multicenter, double-blind, placebo controlled, interventional clinical trial that will be conducted in Poland, in about 6 Hospital Nephrology Departments to evaluate the safety and effectiveness of desmopressin on the prevention of bleeding after percutaneous needle kidney biopsy in patients with rare and ultrarare glomerulonephritis.

Eligibility criteria

Qualifiers

≥ 18 years old

Ability to provide Informed Consent

Qualification by nephrologist to kidney biopsy in accordance to current standards

Initial haemoglobin concentration > 8g/dl and PLT count >100 x103/μL

Disqualifiers

Initial sodium concentration <130mmol/l

Pregnancy and breastfeeding

Anaphylactic shock after desmopressin administration (medical history)

Necessity of administration other anti-platelet / anti thrombotic drugs other than acetylsalicylic acid, non-fractionated heparin or low molecular weight heparin

Trial design

Treatments tested in this trial

  • Desmopressin
  • intravenous infusion NaCl

Treatment groups

424 Participants
are divided into 2 treatment groups