About this trial
It is a randomized, multicenter, double-blind, placebo controlled, interventional clinical trial that will be conducted in Poland, in about 6 Hospital Nephrology Departments to evaluate the safety and effectiveness of desmopressin on the prevention of bleeding after percutaneous needle kidney biopsy in patients with rare and ultrarare glomerulonephritis.
Eligibility criteria
Qualifiers
≥ 18 years old
Ability to provide Informed Consent
Qualification by nephrologist to kidney biopsy in accordance to current standards
Initial haemoglobin concentration > 8g/dl and PLT count >100 x103/μL
Disqualifiers
Initial sodium concentration <130mmol/l
Pregnancy and breastfeeding
Anaphylactic shock after desmopressin administration (medical history)
Necessity of administration other anti-platelet / anti thrombotic drugs other than acetylsalicylic acid, non-fractionated heparin or low molecular weight heparin
Trial design
Treatments tested in this trial
- Desmopressin
- intravenous infusion NaCl