Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18-99
SponsorTata Memorial Hospital
About this trial
Standard Maintenance Therapy versus Local Consolidative Radiation Therapy and standard maintenance therapy in 1-5 sites of OligoMetastatic Non-small cell lung cancer (NSCLC): A Phase III Randomized Controlled Trial
Eligibility criteria
Qualifiers
Age > 18 years
Patients with ECOG performance status of 0-2
Patients with pathologically proven diagnosis of NSCLC
Patients with 1-5 sites of metastatic disease not including the primary tumor and regional nodes (less than or equal to 3 metastatic lesions in one organ will be eligible and 4 or more metastatic lesions in one organ will be ineligible)
Disqualifiers
Patients with progressive disease after initial standard systemic therapy
Patients with oncogene driver mutations
Patients with more than 5 sites of oligo metastases
Patients with metastatic lesion size of more than 5 cm
Trial design
Treatments tested in this trial
- Local consolidative radiation therapy
- Standard maintenance therapy as decided by the treating medical oncologist
Treatment groups
190 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov