Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age12-60
SponsorWomen's Hospital School Of Medicine Zhejiang University

About this trial

Study of hysteroscopic repeat curettage as the first-line treatment in low-risk postmolar gestational trophoblastic neoplasia compared with the MTX single drug chemotherapy

Eligibility criteria

Qualifiers

low-risk postmolar gestational trophoblastic neoplasia (GTN)

World Health Organization(WHO) risk score≤4

Age≤60 years; female, Chinese women

Initial treatment

Disqualifiers

Patients with unconfirmed diagnosis of GTN

Patients with placental-site trophoblastic tumor (PSTT) or epithelioid trophoblastic tumor (ETT)

WHO risk score ≥5分

The diameter of a single metastatic lesion in the lung was ≥2cm

Trial design

Treatments tested in this trial

  • Methotrexate
  • hysteroscopic repeat curettage

Treatment groups

70 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Women's Hospital School Of Medicine Zhejiang University

Lead sponsor

Sun Yat-sen University

Collaborator

Huazhong University of Science and Technology

Collaborator

Qilu Hospital of Shandong University

Collaborator