Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age10-17
SponsorBristol-Myers Squibb

About this trial

The purpose of this study is to evaluate the effectiveness, safety, tolerability, drug levels and drug effects of ozanimod compared to fingolimod in children and adolescents with relapsing remitting multiple sclerosis (RRMS).

Eligibility criteria

Qualifiers

Has a diagnosis of multiple sclerosis (MS) as defined by the 2017 revision of the McDonald Criteria with a relapsing remitting course of disease.

Disqualifiers

Diagnosis of progressive forms of MS.

Active or chronic disease of the immune system other than MS.

Clinically relevant cardiovascular, hepatic, neurological other major systematic disease.

Other protocol-defined Inclusion/Exclusion criteria apply.

Trial design

Treatments tested in this trial

  • Ozanimod
  • Fingolimod
  • Placebo

Treatment groups

194 Participants
are divided into 2 treatment groups

Sponsors and collaborators