Switching to E-cigarettes in Smokers Not Interested in Quitting
ConditionSmoking Reduction
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age21+
SponsorUniversity of Kansas Medical Center
About this trial
The objectives of this application are to 1) compare short- and long-term harm reduction and abuse liability potential of a nicotine salt pod-based electronic cigarettes (EC) in adult (AA) exclusive EC, dual cig-EC, and exclusive cig users, 2) characterize factors that predict who switches fully, partially, or not at all, and 3) examine if harm reduction can be further enhanced by treating dual users with varenicline (VAR) to eliminate cigarette smoking.
Eligibility criteria
Qualifiers
≥ 21 years of age
Smoke >5 cigarettes per day
Smoked cigarettes for > 6 months
Verified smoker (CO > 5 ppm)
Disqualifiers
Interested in quitting smoking
Use of smoking cessation pharmacotherapy in the month prior to enrollment
Use of other tobacco products in past 30 days (i.e., cigarillos, cigars, hookah, smokeless tobacco, pipes)
EC use on > 4 of the past 30 days
Trial design
Treatments tested in this trial
- Varenicline Tartrate
- Placebo
- Electronic cigarette
Treatment groups
500 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov