The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect

Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe George Institute

About this trial

CAPTIVATE is an international, multi-centre, Phase III, adaptive, platform, randomised controlled trial in people with chronic kidney disease (CKD).

CAPTIVATE aims to find the best treatment, or combination of treatments, that slow the progression of CKD so that fewer people develop kidney failure.

CAPTIVATE provides a research platform that allows many treatment-related questions to be answered within a common trial set-up.

Eligibility criteria

Qualifiers

Age ≥ 18 years

Known chronic kidney disease from any cause (eGFR ≥25 mL/min/1.73m2)

Currently receiving standard of care treatment according to treating physician

Eligible for randomisation in at least one recruiting domain-specific appendix

Disqualifiers

Planned to commence kidney replacement therapy or kidney transplant surgery in next 6 months

Life expectancy less than 6 months

Trial design

Treatments tested in this trial

  • Finerenone
  • Placebo Finerenone

Treatment groups

1,000 Participants
are divided into 2 treatment groups

Sponsors and collaborators