The COLchicine and Atrial FIBrillation Trial
ConditionAtrial Fibrillation
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorHerlev and Gentofte Hospital
About this trial
The purpose of this study to investigate the effects of colchicine on atrial fibrillation recurrence and vascular and cardiac function in patients with atrial fibrillation.
Eligibility criteria
Qualifiers
Living address in the Capital Region of Denmark
Age > 18
Diagnosed with paroxysmic/persistent AF.
Planned or acute admission for cardioversion of AF with successful outcome.
Disqualifiers
Colchicine treatment for another cause, e.g. gout
Allergy/hypersensitivity to colchicine
Uncontrolled hypertension (systolic BP >180 mmHg or diastolic BP >110 mmHg)
History of malignancy of any organ system excluding a successfully treated non-metastatic cutaneous squamous cell or basal cell carcinoma, localized prostate cancer and/or localized carcinoma in situ of the cervix
Trial design
Treatments tested in this trial
- Colchicine
- Placebo
Treatment groups
500 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov