The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients
ConditionPolycystic Ovary Syndrome
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexFemale
Age20-45
SponsorCairo University
About this trial
The study aims to evaluate the effects of combination of metformin with NAC in PCOS on biochemical and hormonal parameters.
Eligibility criteria
Qualifiers
Female aged 20 to 45 years old.
Confirmed diagnosis with PCOS according to the 2023 International Evidence-based Guideline for the Assessment and Management of PCOS.
Ability to give informed consent.
Disqualifiers
Hypersensitivity to either metformin or NAC.
Consumption of medications affecting carbohydrate metabolism, such as insulin, sulfonylureas, and taking hormonal analogues two months prior to enrollment.
Hyperprolactinemia, defined as a prolactin level above laboratory reference range.
Diabetes mellitus.
Trial design
Treatments tested in this trial
- N-acetyl cysteine
- Metfomin
Treatment groups
102 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov