Treatment for Giant Cell Arteritis With Tocilizumab and 8 as Compared to 26 Weeks of Prednisone

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age50+
SponsorInsel Gruppe AG, University Hospital Bern

About this trial

The GISCO study plans to determine whether 8-week therapy is just as effective as 26-week cortisone therapy for treating giant cell arteritis

* with tocilizumab, * while using less cortisone.

Eligibility criteria

Qualifiers

Patients diagnosed with giant cell arteritis

Start of tocilizumab treatment at baseline as part of routine clinical practice

Receive ≥ 20 mg/day prednisone (or equivalent) at baseline

Written informed consent

Disqualifiers

Treated with any investigational drug of chemical or biologic nature within a minimum of 30 days or 5 half-lives (whichever is longer) prior to the first dose of tocilizumab.

Trial design

Treatments tested in this trial

  • Prednisone
  • Prednisone

Treatment groups

178 Participants
are divided into 2 treatment groups