About this trial
The purpose of this study is to determine the effectiveness of the EX-CIPN program in reducing the strength of CIPN symptoms and CIPN-related disability and improving the ability to complete everyday activities. This will be done by determining whether it is better to receive the EX-CIPN program or better to receive no additional intervention. To do this, some of the participants in this study will get EX-CIPN and others will receive usual care. Those who receive usual care will be offered EX-CIPN upon study completion. The main question it aims to answer is:
• Is EX-CIPN effective in improving CIPN symptoms for cancer survivors experiencing persistent CIPN?
Participants in both study groups will be asked to:
• Complete assessments at baseline, immediately post-intervention, and 3-months post-intervention
Participants in the EX-CIPN group will be asked to:
* Complete an additional aassessment at 6-months post-intervention * Complete a 10-week remote, individualized exercise program * Receive health coaching calls on weeks 2, 3, 4, 6, and 8 of the intervention * Wear a FitBit throughout the study to track physical activity and promote behaviour change
Eligibility criteria
Qualifiers
diagnosed with any type of cancer
received chemotherapy treatment as part of curative-intent therapy (no minimum dose)
>6 months following chemotherapy completion with no current plans for further chemotherapy
report Grade 1 or higher on the numbness and tingling severity item of the Common Terminology Criteria for Adverse Events (CTCAE) v 5.0
Disqualifiers
currently meeting all recommendations from the physical activity guidelines for cancer survivors
have any neurological conditions influencing cognition (i.e. dementia, Alzheimer's) and preventing safe or appropriate engagement with exercise recommendation
have neuropathy that pre-existed chemotherapy receipt (i.e. diabetic neuropathy)
currently enrolled in other rehabilitation or exercise-based interventions
Trial design
Treatments tested in this trial
- EX-CIPN