Ultra-early STatin in Patients With Aneurysmal subaRachnoid Hemorrhage (Ue-STAR)

Trial statusNot yet recruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe George Institute

About this trial

A researcher-initiated and conducted multicenter, randomized controlled trial aimed at evaluating the efficacy and safety of ultra-early statin therapy in the treatment of acute aneurysmal subarachnoid hemorrhage (aSAH).

Eligibility criteria

Qualifiers

Male or female; Aged ≥18 years

Signs and symptoms presumed aneurysmal subarachnoid hemorrhage, confirmed by radiological evidence

Treatment within 6 h after symptom onset

Disqualifiers

Treatment with statin prior SAH

Non-aSAH (e.g. traumatic subarachnoid hemorrhage, arteriovenous malformation)

Treatment > 6 h after symptom onset

Allergy to statin medications or presence of severe adverse reactions such as abnormal liver function or rhabdomyolysis

Trial design

Treatments tested in this trial

  • Atorvastatin

Treatment groups

522 Participants
are divided into 2 treatment groups

Sponsors and collaborators

The George Institute

Lead sponsor

Tianjin Medical University General Hospital

Collaborator