Ventilation Imaging to Improve the Quality of Life for Patients With Lung Cancer Treated With Radiation Therapy

ConditionLung Cancer
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Sydney

About this trial

This research project is testing a new treatment planning method for patients with lung cancer who will be treated with radiation therapy. This new method is called Computed Tomography (CT) ventilation imaging. It aims to help protect the healthiest parts of patient's lungs from being injured by the radiation therapy. The investigators will determine whether healthy lung sparing can improve the quality of life in these patients.

Eligibility criteria

Qualifiers

Aged 18 years or older.

Eastern Cooperative Oncology Group (ECOG) performance status 0-2.

Histologically proven non-small cell lung cancer.

Stage 3 as determined using the IASLC (International Association for the Study of Lung Cancer) 8th edition lung cancer staging guidelines.

Disqualifiers

Serious medical comorbidities that may contraindicate curative radiotherapy.

Inability to attend full course of radiotherapy or follow-up visits.

A current or former diagnosis of interstitial lung disease.

Prior history of lung cancer within 5 years.

Trial design

Treatments tested in this trial

  • Healthy lung sparing treatment plan

Treatment groups

165 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Sydney

Lead sponsor

Liverpool Hospital

Collaborator

Royal North Shore Hospital

Collaborator

The Alfred

Collaborator

Peter MacCallum Cancer Centre, Australia

Collaborator

Fundacion GenesisCare

Collaborator