About this trial
This research project is testing a new treatment planning method for patients with lung cancer who will be treated with radiation therapy. This new method is called Computed Tomography (CT) ventilation imaging. It aims to help protect the healthiest parts of patient's lungs from being injured by the radiation therapy. The investigators will determine whether healthy lung sparing can improve the quality of life in these patients.
Eligibility criteria
Qualifiers
Aged 18 years or older.
Eastern Cooperative Oncology Group (ECOG) performance status 0-2.
Histologically proven non-small cell lung cancer.
Stage 3 as determined using the IASLC (International Association for the Study of Lung Cancer) 8th edition lung cancer staging guidelines.
Disqualifiers
Serious medical comorbidities that may contraindicate curative radiotherapy.
Inability to attend full course of radiotherapy or follow-up visits.
A current or former diagnosis of interstitial lung disease.
Prior history of lung cancer within 5 years.
Trial design
Treatments tested in this trial
- Healthy lung sparing treatment plan
Treatment groups
Sponsors and collaborators
University of Sydney
Lead sponsor
Liverpool Hospital
Collaborator
Royal North Shore Hospital
Collaborator
The Alfred
Collaborator
Peter MacCallum Cancer Centre, Australia
Collaborator
Fundacion GenesisCare
Collaborator