Health Trials

A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia

ConditionHypotension Drug-Induced
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-80
SponsorDalian Municipal Central Hospital

About this trial

The purpose of this study is to investigate whether norepinephrine(N), phenylephrine(P) or ephedrine(E) have different effect on cerebral oxygenation in abdominal surgery with propofol or sevoflurane.

Eligibility criteria

Qualifiers

ASA I-III, age 18-80 years

Elective abdominal surgery

Signed informed consent

Disqualifiers

ASA≥IV

Preoperative unstable blood hemodynamics

Allergy to ephedrine, phenylephrine or norepinephrine

Decrease in MAP <20%

Trial design

Treatments tested in this trial

  • Ephedrine-P
  • Phenylephrine-P
  • Norepinephrine-P
  • Ephedrine-S
  • Phenylephrine-S
  • Norepinephrine-S

Treatment groups

180 Participants
are divided into 6 treatment groups

6

Treatment groups

See each treatment group below.

Sponsors and collaborators

Dalian Municipal Central Hospital

Lead sponsor

Source ClinicalTrials.gov