The purpose of this research is to determine if two commonly used medications to treat metabolic acidosis in the setting of cardiac surgery, sodium bicarbonate and THAM, are equivalent.
* Cardiothoracic surgery with use of cardiopulmonary bypass
Presence of metabolic acidosis (defined as a base excess of <-5)
Minnesota Research Authorization
Non-cardiac surgery patients or cardiac surgery without cardiopulmonary bypass
Absence of metabolic acidosis (metabolic acidosis being defined as a base excess of <-5)
Pregnant patients
Prisoners