A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to PREVENT ReductioN of DecREased TIMI FLOW in Patients Who Undergoing Percutaneous Coronary Intervention for the Coronary Artery Disease

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age19+
SponsorKorea University Anam Hospital

About this trial

The aim of this study was to determine the effect of intra-coronary administration of nicorandil on the prevention of lowering of coronary blood flow for high-risk plaque lesions defined as the high value of lipid core burden index in patients with coronary artery disease who require stent treatment.

Eligibility criteria

Qualifiers

Over 19 years old

Patients who agree to the study plan and clinical follow-up plan, voluntarily decide to participate in this study, and consent in writing to the consent to use information

Patients who underwent NIRS-IVUS guided coronary stent surgery for coronary artery disease

Disqualifiers

Patients with TIMI ≤ 2 before coronary intervention

Subjects with known hypersensitivity or contraindications to the following drugs or substances: heparin, aspirin, clopidogrel, ticagrelor, prasugrel, rosuvastatin, ezetimibe, evolocumab, lansoprazole, cobalt chromium, stainless steel nickel And contrast agents (however, even a subject who is hypersensitive to contrast agents can register if they can be controlled by steroids and pheniramine, except for known anaphylaxis.)

Pregnant women, lactating women, or women of childbearing age who plan to become pregnant during this study

Subjects who plan to have surgery to stop antiplatelet drugs within 6 months from registration

Trial design

Treatments tested in this trial

  • Nicorandil

Treatment groups

460 Participants
are divided into 2 treatment groups

Sponsors and collaborators