A Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy

ConditionColon Disease
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorAalborg University Hospital

About this trial

The trial is about comparing the efficacy of Plenvu with Picoprep. Both are bowel cleansing agents prior to visual examination of the large bowel to exclude cancer disease.

400 patients who are referred for colonoscopy to a single center in North Jutland will be randomised either to Picoprep or Plenvu. These patients will then answer a questionnaire prior to colonoscopy. The questionnaire is about the most common expected side effects and the experience of cleansing og intake of the bowel agents.

The effect of the two agents will examined using a special scoring system (Harefield) to determine the quality of bowel cleansing. Colonoscopist who evaluate the cleansing is blinded to which agent the patient has taken.

Eligibility criteria

Qualifiers

Ambulant colonoscopy

Older than18

Disqualifiers

Younger than 18

Known with severe heart failure

Known with severe renal failure (eGFR<30)

Known for colonic stenosis

Trial design

Treatments tested in this trial

  • Picoprep
  • Plenvu

Treatment groups

400 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Aalborg University Hospital

Lead sponsor

Regionshospital Nordjylland

Collaborator

Norgine

Collaborator