About this trial
Hepatitis C is a common and potentially serious disease. However, there are treatments that can cure it. That's why it's so important to detect the hepatitis C virus (HCV) and treat those affected. Today, many hepatitis C sufferers in Cameroon (and elsewhere) remain untreated.
The aim of this research is therefore to evaluate a simplified screening and treatment strategy (developed specifically for the Cameroonian context) in comparison with a standard strategy (based on usual care), in order to improve access to hepatitis C treatment in Cameroon. If the results of this research are positive, this strategy could be recommended to health authorities in Cameroon and other comparable countries.
Eligibility criteria
Qualifiers
Persons of both genders aged 21 years or older
Anti-HCV positive;
Living in the study area
Agreeing to participate in the trial and signing the informed consent form.
Disqualifiers
Participationin a previous study on HCV treatment
Previous sofosbuvir treatment
HBsAg positive or indeterminate;
Pregnancy test positive ;
Trial design
Treatments tested in this trial
- ACCESS+ strategy Epclusa 400/100 Oral Tablet
- ACCESS+ Strategy Vosevi 400/100/100 Oral Tablet
- Standard Strategy Vosevi 400/100/100 Oral Tablet
- Standard Strategy Epclusa 400/100 Oral Tablet
Treatment groups
Locations
Sponsors and collaborators
ANRS, Emerging Infectious Diseases
Lead sponsor
IRD, Epidemiologie et Prevention, Montpelier, France
Collaborator
SESSTIM (IRD, Inserm, Université Aix-Marseille)
Collaborator
Centre de Recherche sur les Maladies Emergentes et Re-Emergentes (CREMER)
Collaborator
Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun
Collaborator
PharmAccess
Collaborator
Service d'hépato-gastroentérologie, Hôpital Saint Joseph, Marseille, France
Collaborator