Phase IV, open-label, randomized and multicenter clinical trial to prove that patients with Enterococcus faecalis infective endocarditis treated with an antibiotic treatment as a continuous infusion is non-inferior to the standard treatment, usually administered in hospitalized patients.
Adult patients
Possible or definitive diagnosis of infective endocarditis due to Enterococcus faecalis
Signed informed consent of patients
Allergy to penicillins or cephalosporins
Pregnancy and lactation
Polymicrobial infection including microorganisms different to E. faecalis
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Lead sponsor
Spanish Clinical Research Network - SCReN
Collaborator