Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorR-Evolution Worldwide S.r.l. Impresa Sociale

About this trial

The goal of this clinical trial is to compare the combination albendazole and praziquantel versus albendazole alone in patients affected by neurocysticercosis.

Eligibility criteria

Qualifiers

Living in the study area for a continuous period of 3 years

Adult aged 18 years and above

Are willing and able to consent to this study

Meet the definitions of active symptomatic NCC

Disqualifiers

Women pregnant or breastfeeding

Symptomatic NCC with cysts in extra-parenchymal location (sub-arachnoid and/or ventricles)

Have uncontrolled hypertension and/or diabetes

Have chronic consuming illness such as cancer or mental handicap to not allow them to follow the study instructions

Trial design

Treatments tested in this trial

  • albendazole and praziquantel
  • Albendazole

Treatment groups

300 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

R-Evolution Worldwide S.r.l. Impresa Sociale

Lead sponsor

Muhimbili University of Health and Allied Sciences

Collaborator

National Institute for Medical Research, Tanzania

Collaborator

Sokoine University of Agriculture

Collaborator

University of Zambia

Collaborator

University Ghent

Collaborator