Attenuate the Stress Response in Laparoscopic Cholecystectomy
ConditionLaparoscopic Cholecystectomy Surgery
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAssiut University
About this trial
Aims of this study are to compare the effectiveness of dexmedetomidine versus fentanyl-midazolam in attenuating hemodynamic stress response during laparoscopic cholecystectomy (mainly HR). And to assess the recovery profile, the pain and opioid requirements, the sedation profile, and any adverse events during the first 24 hrs postoperatively
Eligibility criteria
Qualifiers
Age 18-65 years.
Both sexes.
American Society of Anesthesiology (ASA) physical status I - II.
Disqualifiers
Known allergy to study drugs.
Uncontrolled, non-correctable comorbidities (hepatic, renal or cardiac such as hypertension & Arrhythmia ).
History of psychiatric illness or substance abuse.
Pregnancy or lactation
Trial design
Treatments tested in this trial
- Dexmedetomidine
- Fentanyl- midazolam
Treatment groups
50 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov