Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorMahidol University
About this trial
A double-blind randomized controlled trial comparing beta-lactam plus levofloxacin versus beta-lactam monotherapy for the treatment of Streptococcal bacteremia
Eligibility criteria
Qualifiers
Adults age>18 years
Blood culture positive for Streptococcus (<72 hours before enrollment)
at least 1 bottle of S. pyogenes, S. agalactiae, S. pneumoniae, S. suis
at least 2 bottle of other Streptococci
Disqualifiers
Known allergy to beta-lactam or fluroquinolone antibiotics
Pregnancy or lactating mother
EKG with QT prolongation
Diagnosis of infective endocarditis
Trial design
Treatments tested in this trial
- Beta-lactam monotherapy
- Beta-lactam plus levofloxacin combination therapy
Treatment groups
165 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov