Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Kansas Medical Center
About this trial
Investigators hypothesize that topical tranexamic acid will have better or comparable efficacy to topical thrombin in reducing hematoma formation at the wound base. The purpose of the study is to demonstrate that topical tranexamic acid will be a non-inferior alternative medication to the current standard of care,THROMBIN-JMI® , and at a lower cost to the health system.
Eligibility criteria
Qualifiers
English or Spanish speaking
Flame or scald burn injury
<=10% total body surface area (TBSA) partial thickness
<= 5% total body surface area (TBSA) deep partial or full thickness
Disqualifiers
>10% total body surface area (TBSA) partial thickness burn
>5% total body surface area (TBSA )surgical area of burn injury (deep partial or full thickness injury)
Traumatic or chemical burn mechanism
Patients on immunosuppression
Trial design
Treatments tested in this trial
- Tranexamic acid
- Thrombin JMI
- skin graft
Treatment groups
62 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov