Clinical Study of GKT in Diabetes Related Dementia

ConditionDementia
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age60-90
SponsorShanghai 10th People's Hospital

About this trial

Recently a new clinical dementia subgroup based on brain imaging, called "diabetes related dementia (DrD)". DrD, unlike Alzheimer's disease and vascular dementia, is considered a "controllable" or "modifiable" form of dementia. However, there is currently a lack of corresponding treatment measures. Ginkgo biloba ketone ester tablets are extracts of Ginkgo biloba leaves. Previous studies have shown that they can increase cerebral blood flow, reduce cerebrovascular resistance, improve cerebral circulation, and are beneficial for the treatment of cognitive impairment. This project intends to explore the role of ginkgo ketoester tablets in diabetes related dementia through a multicenter randomized double-blind controlled clinical study.

Eligibility criteria

Qualifiers

Type 2 diabetes with mild cognitive impairment patients aged 65 years or above;

Able to cooperate in completing cognitive function testing;

Patients who can swallow pills

No previous history of stroke,cerebral thrombosis, etc

Disqualifiers

Type 1 diabetes;

Acute cerebral infarction and myocardial infarction within 3 months;

Severe liver and kidney dysfunction;

Late stage malignant tumors;

Trial design

Treatments tested in this trial

  • Ginkgo Ketone Ester Tablets
  • placebo

Treatment groups

370 Participants
are divided into 2 treatment groups

Locations

This trial has no locations