About this trial
Lower abdominal surgeries often result in severe pain, which in turn can cause rapid and shallow breathing, retention of secretions and poor patient compliance. Justifiably, apart from the fear for the surgery outcome, patients are concerned mainly with postoperative pain. If treated inadequately, acute pain can have serious consequences for patient health mainly with postoperative complications, prolonged recovery and increased length of hospital stay. Higher levels of postoperative pain and pain distress are associated with increased morbidity, poorer functional recovery, and reduced quality of life.
Aim of the study To compare the duration, quality of analgesia, and side effects between intrathecal Magnesium sulfate, neostigmine and fentanyl as adjuvant for bubivacaine as postoperative analgesia in lower abdominal surgeries
Eligibility criteria
Qualifiers
• the American Society of Anesthesiologists (ASA) classification I-II
Age >18 up to 55 years old
Both sex
Patients who will undergo lower abdominal surgeries
Disqualifiers
• Patients' refusal.
Patients with morbid obesity, cardiac diseases, hepatic diseases, renal diseases, diabetes mellitus with polyneuritis.
Patients who were in risk-scoring groups American Society of Anesthesia III-IV.
Hypertensive patients receiving therapy with adrenergic receptor antagonist, calcium channel blocker and/or angiotensin converting enzyme inhibitor.
Trial design
Treatments tested in this trial
- Magnesium Sulfate and Bupivacaine 0.125%
- bupivacaine and Neostigmine
- fentanyl and bupivacaine