Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age21-60
SponsorNational University Hospital, Singapore

About this trial

This research study is to determine the effectiveness of prednisolone and methotrexate for IGM patients over a period of one year, in terms of clinical and radiological response. Recruitment will be conducted in National University Hospital (NUH) for patients diagnosed with IGM.

Eligibility criteria

Qualifiers

Women, aged between 21 and 60 years

Positive diagnosis of idiopathic granulomatous mastitis based on histopathology results

Willing and able to give informed consent

Disqualifiers

Women who are currently pregnant or breastfeeding

Cognitive impairment which prevents the patient from giving voluntary consent

History of any psychiatric conditions such as depression, psychosis, schizophrenia etc.

History of cancer in the past 5 years

Trial design

Treatments tested in this trial

  • Prednisolone
  • Methotrexate
  • Folic Acid 5 MG
  • Omeprazole 20 mg

Treatment groups

40 Participants
are divided into 2 treatment groups