Comparing Pain Improvement for Intravenous Versus Oral Acetaminophen in Acute Pelvic Pain
ConditionPelvic Pain
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age16-50
SponsorMontefiore Medical Center
About this trial
The investigator team proposes a randomized, double-blind, double-dummy comparative effectiveness trial conducted in two urban emergency departments (EDs) in the Bronx, New York. This study is designed to determine the relative efficacy of IV acetaminophen compared to PO acetaminophen in treating pelvic pain. This design focuses on the early onset of action and short-term efficacy, which may better capture potential differences between IV and PO acetaminophen in the acute ED setting.
Eligibility criteria
Qualifiers
Female sex at birth
Presentation to the Emergency Department (ED) with pelvic pain
Baseline numeric pain score (NRS) ≥4
Ability to provide informed consent in English or Spanish
Disqualifiers
Receipt of any analgesic medication within 2 hours or acetaminophen within 6 hours
Known allergy or intolerance to acetaminophen
Trial design
Treatments tested in this trial
- Acetaminophen 1000mg PO
- IV Acetaminophen 1000mg
- IV Placebo
- PO Placebo
Treatment groups
140 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov