Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia

Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age65-80
SponsorGeneral Hospital of Ningxia Medical University

About this trial

At the initiation of induction for non-intubated general anesthesia, ciprofol or propofol will be administered intravenously at a rate of 10 mL/min. The Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale will be used to evaluate sedation depth. This study aims to assess the effects of ciprofol and propofol on hemodynamics and respiratory function in elderly patients undergoing non-intubated general anesthesia.

Eligibility criteria

Qualifiers

Patients scheduled for elective non-intubated general anesthesia

Age ranging from 65 to 80 years old

American Society of Anesthesiologists (ASA) physical status class I-III

Written informed consent signed by the patient or legal guardian

Disqualifiers

Confirmed allergy to propofol, ciprofol or their excipients

Severe cardiovascular diseases (uncontrolled hypertension, heart failure, severe arrhythmia, etc.)

Severe respiratory diseases (chronic obstructive pulmonary disease, obstructive sleep apnea syndrome, etc.)

Severe hepatic or renal insufficiency

Trial design

Treatments tested in this trial

  • Propofol Injection
  • Ciprofol Injection

Treatment groups

108 Participants
are divided into 2 treatment groups