Comparison of Omeprazole vs Vonoprazon in Treatment of H Pylori Infection
ConditionH Pylori
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age12+
SponsorRehman Medical Institute - RMI
About this trial
Current studies have primarily focused on comparing the advantages and disadvantages of P-CAB and PPI drugs, with little comparison between different P-CAB drugs or between regimens with varying drug combinations and treatment durations.
This study aims to evaluate the clinical effectiveness of vonoprazan-based H. pylori eradication therapy and compare it to that of conventional PPI based therapy in clinical practice.
Eligibility criteria
Qualifiers
All patients who tested positive on stool antigen
Disqualifiers
patients under 12 years old.
Patients who have penicillin allergy.
Patients who have underlying dysrhythmia forbidding the use of macrolide -. Patient who have hypersensitivity to any of these antibiotics or proton pump inhibitors.
Trial design
Treatments tested in this trial
- Clarithromycin 500 mg
- Amoxicillin 1 g
- Omeprazole 40 mg
- Clarithromycin 500 mg
- Amoxicillin 1 g
- Vonoprazan 20 mg
- Levofloxacin 500 mg
- Amoxicillin 1 g
- Omeprazole 40 mg
- Levofloxacin 500 mg
- Amoxicillin 1 g
- Vonoprazan 20 mg
Treatment groups
128 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov