About this trial
The goal of this clinical trial is to learn which one works to treat better in patients with sudden sensorineural hearing loss, oral or intratympanic corticosteroid treatment.
The main question it aims to answer is:
Which corticosteroid treatment is more effective in patients with sudden sensorineural hearing loss, oral or intratympanic?
* In our study, it was planned to divide the treatment schemes compared into two groups. Group 1 included patients who received oral methylprednisolone treatment daily for 2 weeks (48 mg for the first 7 days, 32 mg for the following 2 days, 16 mg for the 2 days, and 8 mg for the last 3 days). Group 2 included patients who received intratympanic 8 mg/2 ml dexamethasone every other day, totally 4 doses. * Visit the clinic after diagnose in first week, second week, first month and second month for checkups and tests ( temporal MR, odimetric results)
Eligibility criteria
Qualifiers
18 years of age and older
Unilateral sudden sensorineural hearing loss that developed within 72 hours and has lasted for 14 days or less
Affected side PTA (500-100-2000-4000hz) should be over 50dB
Affected side should be at least 30dB lower than healthy side in 3 frequencies
Disqualifiers
Having a history of hearing-related surgery other than a ventilation tube
Having a history of previous hearing loss, fluctuating hearing or Meniere's disease, chronic inflammatory or suppurative ear disease or cholesteatoma, otosclerosis
Being under 18 or over 80
Having a history of physical-barotrauma
Trial design
Treatments tested in this trial
- Methylprednisolone (drug)
- Dexamethasone