Comparison of Topical Insulin and Amniotic Membrane Transplant for Persistent Corneal Epithelial Defects

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age16-70
SponsorAl-Shifa Trust Eye Hospital

About this trial

After an initial period of standard treatment, they received further care aimed at helping the surface of the eye heal. Clear instructions were given on how to use and store the treatment properly. Patients were then monitored regularly over several months, with doctors checking their healing progress during follow-up visits. The study continued for a total of 24 weeks to observe how well and how quickly the eye surface recovered.

Eligibility criteria

Qualifiers

Corneal epithelial defects for more than 2 weeks no improvement using standard treatment

Disqualifiers

• Systemic conditions e.g. uncontrolled Diabetes, autoimmune disorders

Recent eye surgery within last 3 months

Hereditary corneal dystrophies

Active eye infections

Trial design

Treatments tested in this trial

  • Topical insulin eye drops
  • Amniotic Membrane Graft

Treatment groups

214 Participants
are divided into 2 treatment groups

Sponsors and collaborators