Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
ConditionCongenital Heart Disease in Children
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age3-59
SponsorPhoenix Children's Hospital
About this trial
The proposed study will be a prospective, randomized, double blind, placebo controlled trial to compare the use of a continuous infusion versus intermittent ketorolac on postoperative patients in the pediatric cardiovascular ICU. We intend to determine if the continuous infusion leads to a decreased utilization of opiates when compared to intermittent ketorolac.
Eligibility criteria
Qualifiers
All patients aged 3 months to 4 years 11months admitted post operatively to the CVICU during the time period in which the study will be ongoing
Initiation of study medication within the first 12-24 hours post-operatively
The cardiovascular attending of record after review of the intraoperative course and post-operative laboratories determines the patient will receive Ketorolac for pain control
Disqualifiers
Patients that have acute kidney injury, as defined by the letter "I" in the pRIFLE criteria.
History of allergy or sensitivity reaction to ketorolac or any NSAID medications.
Requiring mechanical circulatory support (ECMO) or continuous renal replacement therapy (CRRT) within the first 48 hours post-operatively
Orthotopic heart transplantation
Trial design
Treatments tested in this trial
- Continuous ketorolac
Treatment groups
166 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov