About this trial
The purpose of this trial is to evaluate if the use of Bone Morphogenic Protein(BMP)/Demineralized Bone Matrix (DBM) versus the use of autologous Iliac Crest Bone Graft (ICBG) will result in an increase in total cost effectiveness for patients undergoing alveolar bone graft (ABG) for Cleft Lip and Palate (CLP) and to see if patients who are treated with DBM/BMP will have reduced post-operative pain scores,reduced operative times,and similar rates of bone healing compared to conventional ICBG.
Eligibility criteria
Qualifiers
Patient with CLP(unilateral or bilateral)
Radiographically evident open bone defect of the alveolus
Dentition evaluated by orthodontist and cleared for ABG surgery
Disqualifiers
Patients without CLP
Previous failed repair of alveolar cleft
Patients who have previously undergone successful ABG
Patients without an alveolar defect
Trial design
Treatments tested in this trial
- Intervention group (DBM/BMP)
- Control group(autologous ICBG)