Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial

Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18-65
SponsorRawalpindi Institute of Cardiology

About this trial

After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication. Each participant will receive a unique study number to protect privacy. Participants will be randomly assigned to receive one of the study medications using a chance-based method.The study medication will be administered through a vein before placement of the breathing tube. Blood pressure and pulse rate will be measured before the procedure and at several time points after the breathing tube is inserted.

Eligibility criteria

Qualifiers

None

Disqualifiers

Patients with known hypersensitivity to dexmedetomidine and Lignocaine.

Patients on medications that could interfere with the study (e.g., beta-blockers, calcium channel blockers).

Pregnant or lactating women.

Patients with a history of airway anomalies or difficult intubation.

Trial design

Treatments tested in this trial

  • IV dexmedetomidine
  • IV Lignocaine

Treatment groups

70 Participants
are divided into 2 treatment groups