Disentangling the Effects of Daily Stress, Sleep, and Sex Hormones on Accelerated Vascular Aging in Midlife Women
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexFemale
Age40-55
SponsorUniversity of Delaware
About this trial
The purpose of this study is to identify the impact of estradiol (E2) on the associations between (a) responsivity to daily stress or (b) sleep variability with vascular function in midlife premenopausal women.
Eligibility criteria
Qualifiers
Female
Age 40-55
Premenopausal
Disqualifiers
Pregnancy (including a positive urine pregnancy test), planning to become pregnant, or breast-feeding
Peri- or post-menopausal
Unstable or diagnosed chronic clinical disease, including cardiovascular, metabolic, renal, hepatic, autonomic, autoimmune, or dermatological disease
Current or lifetime major psychiatric illness (e.g., major depressive disorder, bipolar disorder, schizophrenia, eating disorders)
Trial design
Treatments tested in this trial
- ganirelix acetate
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Delaware
Lead sponsor
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov