The DMEC trial is a randomized clinical two-arm trial comparing inflammation and cystoid macular edema for the medication regimens postoperative topical NSAIDs and steroids to only postoperative topical steroids in patients undergoing corneal endothelial transplantations (DSAEK or DMEK).
Patients must be 18 years and older at the time of the signing of the informed consent. There is no upper age limit.
Scheduled for DSAEK or DMEK
Ability to cooperate fairly well during the examinations
Willing to participate in the study and capable of giving informed consent, which includes compliance with the requirements and restrictions in the informed consent form (ICF) and in this protocol.
Contraindications for use of any medication (as listed in the approved SPC, e.g. allergy, pregnancy, breastfeeding)
Pregnancy or possible pregnancy during the study period
Preoperative macular edema and/or ongoing treatment for macular edema
Re-transplantation