Duloxetine for Perioperative Pain in Hip Arthroplasty: A RCT
ConditionTHA
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Miami
About this trial
The primary objective of this study is to compare total narcotic intake standardized via milligram morphine equivalents between duloxetine and placebo cohorts after a total hip arthroplasty.
Eligibility criteria
Qualifiers
Patients > 18 years of age
Patients undergoing primary total hip arthroplasty
Ambulatory patient prior to fracture
Subjects must be capable of providing informed consent
Disqualifiers
Previous hemiarthroplasty or THA on ipsilateral hip
History of Complex Regional Pain Syndrome in ipsilateral extremity
History of demyelinating disorder or neurologic deficit that may contribute to altered pain tolerance or sensation
Acute or chronic hip infection in ipsilateral extremity
Trial design
Treatments tested in this trial
- Duloxetine
- Placebo
Treatment groups
64 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov