Previous study showed that the proportions of hemorrhagic Infarction after intravenous thrombolysis were 24.2% and 32.5% in the control group and the alteplase group, and most of them were asymptomatic. Hemorrhagic Infarction was a part of the natural progression after acute ischemic stroke. Previous study have shown no significant relationship between hemorrhagic Infarction and poor outcome in acute ischemic stroke (AIS) patients. In this study, a randomized controlled trial will be conducted to explore the efficacy and safety of early antiplatelet therapy after hemorrhagic infarction in acute ischemic stroke treated with intravenous thrombolysis.
Acute ischemic patients receiving intravenous thrombolysis within 24 hours upon stroke onset
Be confirmed as Hemorrhagic Infarction at 24 to 36 hours after intravenous thrombolysis by computerized tomography
The patient or family member signed an informed consent
Early use of anticoagulant drugs within 1 week after intravenous thrombolysis;
Tirofiban was used after receiving endovascular treatment;
Intraoperative stent placement after receiving endovascular treatment;
Subarachnoid hemorrhage or ventricular hemorrhage;
Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead sponsor
Shaoxing People's Hospital
Collaborator
Affiliated Hospital of Jiaxing University
Collaborator
Huzhou Central Hospital
Collaborator
The Second Affiliated Hospital of Jiaxing University
Collaborator
Jinhua Central Hospital
Collaborator
Taizhou Hospital
Collaborator
Ningbo Medical Center Lihuili Hospital
Collaborator
Ningbo No.2 Hospital
Collaborator
Lishui Country People's Hospital
Collaborator
Wenzhou Central Hospital
Collaborator
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Collaborator
Shenzhen Second People's Hospital
Collaborator
The Affiliated Hospital of Xuzhou Medical University
Collaborator