Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorKocaeli City Hospital
About this trial
This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated. Patients managed with three different anesthesia methods currently used will be examined for recovery patterns:
1. Total intravenous anesthesia (TIVA), 2. TIVA Combined anesthesia with sevoflurane and intravenous agents (sevoflurane-CIVIA), 3. TIVA Combined anesthesia with desflurane and intravenous agents (desflurane-CIVIA).
Recovery patterns include; extubation time, eye opening time, emergence agitation, postoperative nausia and vomiting and postoperative recovery unit discharge time.
Eligibility criteria
Qualifiers
Scheduled for spine surgery
Expected surgery duration longer than 3 hours
Use of intraoperative neuromonitoring
BIS-guided anesthesia administered
Disqualifiers
Emergency surgeries
Patients receiving sole inhaled anesthesia (no TIVA)
Perioperative dural injury
Intraoperative severe hypotension requiring inotropic support
Trial design
Treatments tested in this trial
- Sevofluorane
- Desflurane
- Total Intravenous Anesthesia(TIVA)
Treatment groups
210 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov