This study uses a prospective, up-and-down sequential allocation method to determine the median effective dose (ED50) and 95% effective dose (ED95) of alfentanil combined with propofol for successful laryngeal mask airway (LMA) insertion in children aged 7-12 undergoing elective day surgery.
Aged 7 to 12 years
Undergoing elective day surgery
ASA physical status I-II
Body Mass Index (BMI) between 14 and 24 kg/m²
Allergy to opioids
Unresolved upper respiratory tract infection within the past 1 week
Abnormal heart, lung, liver, or kidney function, or metabolic diseases
Airway anatomical abnormalities (e.g., micrognathia, laryngomalacia, macroglossia) or OSAHS (Obstructive Sleep Apnea-Hypopnea Syndrome)