The goal of this clinical trial is to evaluate the efficacy and safety of liposomal Bupivacaine administered by paravertebral block for the treatment of acute and chronic pain after video-assisted thoracoscopic lobectomy.
Participants who scheduled for elective video-assisted thoracoscopic lobectomy under general anesthesia.
Participants were 18 years or older.
18 kg/m2≤BMI≤30 kg/m2
Participants with American Society of Anesthesiology (ASA) physical status I-III.
with severe cardiovascular and cerebrovascular diseases such as myocardial infarction,unstable angina pectoris,severe cardiac rhythm disorders (second- and third-degree heart block,etc.), New York Heart Association (NYHA) functional class III/IV,Ischemic stroke.
with psychiatric disorders (such as schizophrenia,depression,etc.) and cognitive impairment.
with sensory disorders such as hyperalgesia.
with other bodily pain.
The Second Affiliated Hospital of Chongqing Medical University
Lead sponsor
People's Hospital of Chongqing
Collaborator
LanZhou University
Collaborator
Xiangya Hospital of Central South University
Collaborator
Shapingba District People's Hospital of Chongqing
Collaborator