Efficacy of Methylprednisolone for Pain Control After ACL Repair
Trial statusRecruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age13-50
SponsorSt. Louis University
About this trial
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine if this results in decreased postoperative pain and opioid use without increasing complications.
Eligibility criteria
Qualifiers
Patient undergoing ACL repair or ACL reconstruction with tendon autograft
Age 13-50 years old
Able to provide informed consent or parent/legal guardian is able for minors
Disqualifiers
Concurrent and significant injury to other bones or organs (Injury Severity Score of 4 or greater)
Revision ACL reconstruction
Concomitant additional ligament reconstruction or high tibial osteotomy
A history of alcohol abuse, substance abuse or chronic opioid use (filled opioid medication ×2 within 6 months of the surgery)
Trial design
Treatments tested in this trial
- Meloxicam 15 mg
- Medrol 4 MG Oral Tablet Includes Medrol Dosepak
- Gabapentin 300 mg
- Hydrocodone 5Mg/Acetaminophen 325Mg Tab
- Ketorolac 10 Mg Oral Tablet
Treatment groups
90 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov