About this trial
Current literature on platelet rich fibrin (PRF) use in apicoectomies, also known as endodontic microsurgery, is sparse. PRF use in oral surgery or periodontal surgery has been more thoroughly researched. Whether it is able to reduce post-op pain or if it improves success rate in endodontic microsurgery is not well known. It is also not well known if it will be able to increase the rate of healing. This study will evaluate the success of endodontic microsurgery with and without PRF.
Eligibility criteria
Qualifiers
Maxillary or Mandibular Anterior teeth and premolars #4-13 and #20-29 with a history of failing RCT and a periapical radiolucency will be accepted
Disqualifiers
Patients with vertical root fractures
Patients with non-restorable teeth
Patients with class 3 mobility
Pregnant
Trial design
Treatments tested in this trial
- Platelet rich fibrin
Treatment groups
Sponsors and collaborators
Mark Schachman
Lead sponsor
University of Kentucky
Sponsor institution